Reading inner values

for the big picture



  • Innovative, easy-to-use telemetric ICP sensor1,2
  • Multifunctional use for diagnosis and therapy support2,3
  • Improvement of clinical symptoms in up to 75% of shunt patients through effective therapy adjustments with M.scio support2,4
  • Savings potential of 69% in treatment costs for hydrocephalus patients4
  • Optimized patient management through reduction in the number of shunt revisions, diagnostic procedures and hospitalizations4-6
  • Stable long-term implant with high life time7,8  
  • Display of detailed pressure curves due to high sampling rate
    of 44 Hz2,5
  • Puncturability of the silicone membrane (M.scio dome variants)3,5
  • Reliable readings due to low drift of < 2 mmHg / 4 years7
  • MR conditional up to 3 Tesla9



Hydrocephalus and subarachnoid hemorrhages may be associated with a life-threatening increase in intracranial pressure (ICP). Determining the ICP is an important requirement for proper application of ICP-lowering measures.10 To date, there is no way to adequately determine intracranial pressures based on symptoms or imaging methods alone.11,12

In addition to measurement for initial diagnosis, it may be necessary to monitor intracranial pressure repeatedly over a period of years to ensure the desired therapeutic outcome. The information gathered can help prevent time-consuming and costly examinations and hospitalizations, thus improving patient well-being.2,4,5

The M.scio is a long-term implant for simple, non-invasive telemetric measurement of intracranial pressure.


From diagnosis to therapy

The M.scio can be used for diagnosis as well as for therapy support.

It can be implanted to determine intracranial pressure for diagnostic purposes.3 Moreover, the M.scio can also be integrated into a shunt to determine the ICP in the shunt.2-4 This allows conclusions to be drawn about the functionality of the shunt system and may help to steer treatment in a positive direction.2

M.scio without shunt system


M.scio with shunt system




The M.scio makes it possible to measure and evaluate intracranial pressure non-invasively. The results can then be incorporated into diagnostic and therapeutic decisions. It is an advanced version of the SENSOR RESERVOIR.

Pressure is measured via a measuring cell located inside the M.scio. The electronics for pressure measurement are protected by the titanium housing of the measuring cell against external, negative influences that could impair its function - for a high functional reliability and a long service life.

The housing of the M.scio is made of the biocompatible polymer PEEK. The materials used are of the highest-quality and have been tested and standardized for use as implant materials. The catheters are made of silicone and are latex-free.

The M.scio is available in four variants: dome-angled, flat-angled, dome-inline, and flat-inline. Both “dome” variants fulfill the characteristics of a conventional reservoir in addition to intracranial pressure measurement. This means they allow therapeutic pressure relief through withdrawal of cerebrospinal fluid (CSF), diagnostic sampling of CSF, administration of fluids, and verification of pressure readings.




Reader Unit Set

The pressure values of the M.scio can be read out by the attending physicians with the help of the Reader Unit Set. The measured values are displayed and automatically stored with date and time on an SD card. For later detailed analysis, the data and curve progressions can be recalled with the Reader Unit Set and evaluated on a PC with ICPicture for further processing for research purposes.


measuring modes

Three measuring modes are available for recording pressure values with the Reader Unit Set.


With the single measurement, the pressure value measured at a point is displayed as a single measured value.
The measuring unit of the pressure value can be selected in the settings.


During the continuous measurement, sequential single measurements are performed and the recorded measured values are displayed as a curve. The interval between the single measurements can be adjusted in the settings in the range from 1 to 300 seconds.


With the fast measurement, sequential single measurements are recorded at a high sampling rate (44 measurements per second) and displayed as a curve.

Quality Reference

A user survey within the scope of the clinical follow-up (PMCF study) for the predecessor SENSOR RESERVOIR impressively proves the long-term stability and quality of the telemetric pressure sensors.


This survey was conducted in 2019 and contains feedback on a total of 284 implanted pressure sensors.


95% (270) of the pressure sensors were still implanted in the patients at the time of the survey - without malfunction, many of them for more than three years.


100% of the users of the pressure sensors have evaluated it as a helpful product and an advantageous addition in the treatment of hydrocephalus.




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Miethke Journal

The MIETHKE Journal is a platform for a broad spectrum of technologies and questions that doctors and patients inevitably encounter at some point in the treatment of hydrocephalus with shunt systems.
Hydrocephalus is our topic. Every day. Full-time.


Thoralf Knitter

Director Product Development

Roland Schulz

Director Product Management

Thammo Weise

Product Management

Andreas Bunge

Product Management

Michaela Funk-Neubarth

Head of Marketing & HR

Jan Mügel

Product Management

Josefine Kehl

Deputy Director Marketing

August von Hardenberg

Management Consultant

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B. Braun and MIETHKE - Together for a better life with hydrocephalus

We have a long and intensive partnership with B. Braun in the field of neurosurgery. We are driven by a common vision: to improve the lives of hydrocephalus patients around the world with innovative solutions.

Our partnership is an exciting combination of B. Braun's nearly 180 years of expertise as one of the world's leading medical device and pharmaceutical companies and our agility as an innovative company and technology leader in gravitation-based shunt technology. 


Our strong partner in neurosurgery:



(1) Ertl P, Hermann EJ, Heissler HE, et al. Telemetric Intracranial Pressure Recording via a Shunt System Integrated Sensor: A Safety and Feasibility Study. J Neurol Surg A Cent Eur Neurosurg 2017;78(6):572-5.

(2) Antes S, Stadie A, Muller S, et al. Intracranial Pressure-Guided Shunt Valve Adjustments with the Miethke Sensor Reservoir. World Neurosurg 2018;109:e642-e50.

(3) Pennacchietti, V.; Prinz, V.; Schaumann, A.; Finger, T.; Schulz, M.; Thomale, U. W. Single center experiences with telemetric intracranial pressure measurements in patients with CSF circulation disturbances. Acta neurochirurgica 2020[cited 2022 Apr 28];162(10):2487-97. Available from: https://doi.org/10.1007/s00701-020-04421-7

(4) Bjornson, A.; Henderson, D.; Lawrence, E.; McMullan, J.; Ushewokunze, S. The Sensor Reservoir-does it change management? Acta neurochirurgica 2021[cited 2022 Apr 28];163(4):1087-95. Available from: https://doi.org/10.1007/s00701-021-04729-y

(5) Norager NH, Lilja-Cyron A, Hansen TS, et al. Deciding on Appropriate Telemetric Intracranial Pressure Monitoring System. World Neurosurg 2019;126:564-9.

(6) Thompson S, Thorne L, Toma A, et al. Telemetric monitoring of ICP within a shunt system. A single centre experience including the first in vivo comparison versus conventional intraparenchymal monitoring. Fluids Barriers CNS. 2017;14(Suppl 1):A63.

(7) MIETHKE Bench-Test

(8) PMCF-Survey 2019

 (9) Shellock FG, Knebel J, Prat AD. Evaluation of MRI issues for a new neurological implant, the Sensor Reservoir. Magn Reson Imaging 2013;31(7):1245-50.

(10) Huttner H et al.,IntrakraniellerDruck (ICP), S1-Leitlinie,2018 in: Deutsche Gesellschaft für Neurologie(Hrsg.),Leitlinien für Diagnostik und Therapie in der Neurologie. Available from: www.dgn.org/leitlinien [cited 2022 Apr 28].

(11) Evensen KB, Eide PK. Measuring intracranial pressure by invasive, less invasive or non-invasive means: limitations and avenues for improvement. Fluids Barriers CNS. 2020[cited 2022 Apr 28];17 (1):34. Available from: https://doi.org/10.1186/s12987-020-00195-3

(12) Le Roux P. Intracranial Pressure Monitoring and Intracranial Pressure Monitoring and Management. In: Laskowitz D, Grant G, editors. Translational Research in Traumatic Brain Injury. Boca Raton (FL): CRC Press/Taylor and Francis Group; 2016. [cited 2022 Apr 28] Available from: https://www.ncbi.nlm.nih.gov/books/NBK326713/